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To identify and elucidate the formation pathways
of newly formed compounds in the various food matrices and in the different
processing/cooking conditions.
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To develop and optimise analytical
protocols for the quantification on new markers of thermal treatment and for
health-promoting compounds.
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To develop reliable methods to identify and
quantify the known as well as the new compounds.
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To suggest appropriate
modification in the EU regulations and industrial practices for improving
traceability and safety of thermally treated foods.
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To assess the risk
related to the intake of potentially toxic compounds as well as to assess
the health benefits of other compounds by toxicological and epidemiological
studies.
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To quantify hazardous compounds in European staple foods and to
correlate this data with the cancer incidence.
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To design processing
conditions able to reduce the concentrations of hazardous/toxic compounds to
as low as reasonably achievable and able to increase the concentration of
health-promoting compounds.
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To test possible strategies for the reduction
of acrylamide formation in potato chips.
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To inform and educate consumers
and producers.
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To develop new ingredients, tailored for each food
preparation, that will be the basis for a new generation of functional
foods.
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To elucidate the intestinal absorption and prebiotic effects of
compounds formed by thermal treatment in foods and their effects on the
absorption of other micronutrients.
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To investigate at molecular level the
transduction pathways following the interaction of dietary compounds with AGEs receptors.
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To elucidate the effects of diet on protein modification
in vivo and the implications for health/disease and aging.
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To study in
real food the in vitro evidence concerning HA reduction by antioxidants.
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To test the effect of isolated compounds on the liver detoxification systems.
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To study the significance of AGEs accumulation in nephropathy and liver
dysfunction.
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To elucidate the physiological effect of the in vivo glycation for different proteins and enzymes.